Railison

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Railison ,

I don’t understand your point but it seems interesting. Could you rephrase?

Railison ,

Oh we already know this. There are parts of the genome that, if even slightly changed, cause terrible, terrible things.

Mutations can happen anywhere, but serious mutations (that may affect the basic things a cell needs to do in order to exist) result in cell death and therefore don’t manifest in the population — the population continues on as though the mutation had never existed.

In this way, natural selection conserves some parts of the genome while less essential parts can vary more freely without being deleterious to the organism.

For example, most non-bacteria (including all plants, animals, fungi, protists) have special proteins called histones. Histones are used to package the DNA together and wrap it all up. Cells can’t function at all without a these proteins, and the most important histone proteins evolve so slowly that they’re almost identical between a human and a pea. (Humans and peas shared a common ancestor over half a billion years ago.)

ETA: My molecular biology knowledge is rusty, but IIRC the way DNA is packaged and unpackaged can also reduce or increase the risk of DNA being exposed to potential mutagens. So if it’s wrapped up, it’s harder to access and tamper with

Railison ,

As a fun aside, the Americans and Russians both experimented with this idea during the Cold War. Check out YouTube for some info on the designs

Railison ,

Baroque music sounds absolutely shit. Composers try to mix in so many different voices that it’s the musical equivalent of a TV panel show where everyone is shouting over one another.

On that note: harpsichords in ensembles are background noise at best and very few people would notice their absence.

Railison ,

In the 2000s she was in Melbourne and opened up the new royal children’s hospital. She also opened the original royal children’s hospital.

Imagine being so old that the hospital, built when you were an adult, was so old it was no longer fit for purpose. Metaphor!

Railison ,

There are the ones whose habitats were burned down/deforested. Then there are the ones with raging chlamydia infections. Then there are the ones that are overpopulating their habitat.

Railison ,

As a local I smile seeing lorikeets and kookaburras, but rosellas are very rare where I am and I have to do a double take

Railison ,

Wait till you get chased by one

Railison ,

I’ve been using AirPods Pro for sleeping and, aside from the low battery tone, they’re amazing for this.

Earbuds don’t cancel noise as well as the over-ear models, but you can keep them in your pocket and use them wherever you are.

Railison ,

I love the tiling interface. I haven’t touched it since they decided to start developing COSMIC though.

I’m gonna wait until they get everything up to date before I use it again.

Railison ,

You can actually see their rush to deliver those packages on time

Railison ,

Wouldn’t be surprised if this was due to us just lacking the expertise and equipment to do certain tasks. For example, equipment and people to handle the reactor core.

Railison ,

How dare you mention this without linking!

Railison ,

“Welcome to the first day of the rest of your life”

Railison ,

Our economy is controlled such that we keep a percentage of workers unemployed to limit inflation.

Therefore, there are a number of workers who are unemployed for structural reasons; taking one for the team.

Then, why are we so mean to them?

Railison ,

In Australia, being a total bastard is a good thing, while being a bit of a bastard isn’t so good.

Mad cunt = good. Shit cunt = bad, see image

https://aussie.zone/pictrs/image/66da96fd-750e-41b9-9860-46527390a369.jpeg

If you could take a single character out of a piece of media (book, film, TV show, video game, etc) who would it be?

They would lose any magical powers they may have had in the book, but anything they are, rather than can do, will stay. For example people from the His Dark Materials world would keep their daemons. You can take them out at any time in the story's plot, but for all other people consuming the media, it will be shown that the...

Railison ,

I’m surprised this comment is all the way down!

Railison ,

When I was a kid I remember being confused at what the installation questions were.

If I were my own parent, I’d explain how the OS can sort itself (FHS, Windows, macOS). This gives confidence for installing and inspecting software.

Next, I’d explain how drives work and how they’re represented in different systems. That means partitions and formatting too.

That would then take me to explaining what’s involved in OS installs, erasing everything, dual booting, retaining personal files, etc.

Railison ,

Let the break it, and like other things in life, make (teach) them fix it if they want to keep using it.

Railison ,

Separate to idiotic moves to make standalone software phone home, we do need to have updated laws that deal with products and services that depends on third party infrastructure to exist.

For example, many cloud dependent “smart” home products have been crippled or bricked by their vendors disabling or limiting cloud services. In those cases, consumers deserve a remedy if the change happens soon enough after purchase.

And should vendors be required to open their hardware once it exits support?

Railison ,

Covid?

On a related note, someone I know who works in education jokes that the number one cure for disability in students is graduation.

Railison ,

I’m looking forward to the Pop! team getting this out so they can focus on getting the rest of their distro up to date.

Railison ,

The separate counter for 10,000 does my head in

Railison ,

Things would be so much better if even the current laws and rules were enforced correctly.

Railison ,

So is this Oracle’s fault for over promising, council’s fault for not communicating its needs, or a lack of training/induction?

Railison ,

There are some gaps in this video owing to the guy not knowing some different keyboard shortcuts in macOS and just assuming they don’t exist.

I’d say macOS is still more consistent than Linux but it certainly peaked in Snow Leopard.

Railison ,

The radio station that plays the old hits has started playing newer hits. Spoiler: they’re not new.

Railison ,

In my own case I’d put it down to Flatpak etc. finally resolving the software installation problem.

Installing most Linux OSes has been easy enough for decades, but a program not in your distro’s repos could be a nightmare to get working.

Railison ,

Memories 🥲

Railison ,

I keep finding myself drifting back to XFCE

Railison ,

More than real estate ownership: real estate speculation as an investment strategy

Railison ,

You’re entitled to your opinion and I’m entitled to eviscerate your opinion if it is my opinion that it’s shit.

Though I try to debate ideas with logic and evidence.

Railison ,

My default is to respect all people. It’s on you to lose my respect.

Railison ,

And the MATE user management app can be downloaded and installed on XFCE, works quite well

Railison ,

One way I do TeX now is a few templates (letter, memo, etc) and circulate files in PDF.

If you must use Word to circulate files, consider Pandoc as a way to get them out.

Railison ,

Remember that your beliefs and values should inform your political affiliation, not the other way around.

Don’t let others tell you what you “should” believe, because political views can be nuanced and contextual.

Railison ,

But think of all the calories they’ve given to us! /s

Railison ,

I don’t get the whole rebrand every time the system is implemented. Why not say Go Card+ or something for the new version while the old cards phase out

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